Study to see if using nepafenac 0.1 percentage eyedrop before cataract surgery helps in keeping pupil dilated during procedure and prevents in swelling in retina

Study to evaluate effectiveness of prophylactic topical nepafenac 0.1 percentage in maintaining transoperative mydriasis and preventing post operative macular edema in topical phacoemulsification cataract surgery - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087123

Enrollment

Registered

2025-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H598- Other intraoperative and postprocedural complications and disorders of eye and adnexa, not elsewhere classified

Interventions

Intervention1: Topical Nepafenac 0.1%: Using Topical Nepafenac 0.1% preoperatively in patients undergoing phacoemulsification cataract surgery Control Intervention1: NIL: NA Control Intervention2: con

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosed with senile and/or metabolic cataract. 2. Scheduled for surgery by phacoemulsification. 3. patient With a normal fundoscopy exam, if observance was possible.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or breastfeeding. 2. History of ocular inflammatory or infectious eye disease. 3. Treatment for eye infection within 30 days prior to inclusion in the study. 4. Alterations on the eye surface, including dry eye. 5. History of ocular surgery and/or trauma. 6. Knowledge or suspicion of allergy or hypersensitivity to the preservatives, steroids, topical NSAIDs, or any other component of the study medication.

Design outcomes

Primary

Measure	Time frame
We expect significant results/outcomes that in order to maintain transoperative mydriasis & avoid post-operative macular edema following cataract surgery, prophylactic tropical nepafenac is likely to be usefulTimepoint: Assessment will be done after one and half months.	—

Secondary

Measure	Time frame
NILTimepoint: NA	—

Countries

India

Contacts

Public ContactDr Pravin Tidake

Datta Meghe Institute of Higher Education and Research

drpravinktidake75@gmail.com7887476011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026