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Long term neurocognitive effects on patients with tuberculous meningitis after treatment completion

Residual neurological sequalae and cognitive dysfunction in treated patients of tuberculous meningitis. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/087122
Enrollment
50
Registered
2025-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A170- Tuberculous meningitis

Interventions

Intervention1: Nil: Nil

Sponsors

Maulana azad medical college new delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adults above 18 years of age 2.Diagnosis of TBM- definite or probable TBM cases as per Ahuja criteria 3.Completed anti-tuberculous therapy atleast 1 month ago

Exclusion criteria

Exclusion criteria: 1.Meningitis of other etiologies 2.Age above 80 years 3.HIV 4.Active alcohol or drug abuse 5.Prior stroke, head injury, intracranial hemorrhage or intracranial surgery 6.Drug resistant TB 7.Pre-existing neurological or major psychiatric illness

Design outcomes

Primary

MeasureTime frame
1.Proportions of patients of treated TBM having residual neurological anf cognitive deficits 2.Severity of cognitive impairment as assessed by MMSE and MoCA scoresTimepoint: Baseline—

Secondary

MeasureTime frame
1.Mean level of neurological disability as assessed by modified Rankin scale 2.Proportion of patients having residual radiological, ophthalmological and electrophysiological sequelae 3.Association baseline features of TBM with residual neurological and cognitive deficitsTimepoint: Baseline—

Countries

India

Contacts

Public ContactDRSUMEET SINGLA

Maulana Azad Medical College

sumeetsingla555@gmail.com9810104431

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026