A study to see effect of High Definition Transcranial Direct Current Stimulation compared to sham stimulation in patients suffering from OCD.

Effect of Adjunctive High-Definition Transcranial Direct Current Stimulation in Treatment of OCD-A Double Blinded Randomized Sham-Controlled Study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087103

Enrollment

Registered

2025-05-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F42- Obsessive-compulsive disorder

Interventions

Intervention1: Active High-Definition Transcranial Direct Current Stimulation [HD-TDCS]: Active HD-tDCS group: Will receive 10 sessions (2 per day) over 5 days, 2mA current and for 20 minutes in each

0.2mA current and for 20 minutes in each session that is spaced over at least 3 hours. The electrodes will be positioned as per 10-20 international electrode placement. The anodal electrode will be

Eligibility

Inclusion criteria

Inclusion criteria: 1)Diagnosis of OCD as per ICD-10-DCR criteria. 2)Score of 16 or above on Y-BOCS 3)Right handedness ascertained by Edinburgh handedness inventory. 4)Provides written informed consent for participation in the study

Exclusion criteria

Exclusion criteria: 1)Presence of any other psychiatric disorder, organic mental disorder, or mental retardation. 2)Known substance dependence other than caffeine or nicotine. 3)Presence of any unstable medical or psychiatric condition requiring urgent priority management. 4)Has received electro-convulsive therapy or any other neuro-stimulation in last three months. 5)Patients with metal in cranium, pacemaker in-situ, history of significant traumatic brain injury, epilepsy or cerebrovascular accident. 6)Pregnant or breast-feeding mothers. 7)Presence of skin problems, such as dermatitis, psoriasis or eczema over the scalp. 8)History of serious adverse event following transcranial electric or magnetic stimulation in the past.

Design outcomes

Primary

Measure	Time frame
The difference in YBOCS scores in active and sham groupTimepoint: 1)Baseline: Just Before the delivery of first session (Day 0) 2)After Completion of 10 sessions of HD-TDCS (day 5) 3)Follow-up: After 4 weeks from the day of last session	—

Secondary

Measure	Time frame
The difference in MADRS scores and GAD-7 Item scores in active and sham groupTimepoint: 1)Baseline: Just Before the delivery of first session (Day 0) 2)After Completion of 10 sessions of HD-TDCS (day 5) 3)Follow-up: After 4 weeks from the day of last session	—

Countries

India

Contacts

Public ContactDr Aditya Somani

AIIMS Raipur

dr.adityasomani@gmail.com9592916918

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026