Comparison Of Postoperative Pain Relief Following Intraperitoneal Deposition Of Levobupivacaine With And Without Dexmedetomedine In Laparoscopic Cholecystectomy

Comparison of Postoperative Analgesia Following Intraperitoneal Instillation of Levobupivacaine With And Without Dexmedetomedine In Patient Undergoing Laparoscopic Cholecystectomy - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087082

Enrollment

Registered

2025-05-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Levobupivacaine with Dexmedetomidine: 40ml of 0.25% levobupivacaine with 1mcg/kg of dexmedetomidine will be instilled intraperitoneally through the trocar before the closure of abdomen

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II Patient undergoing laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: 1.ASA III & IV 2.History of allergy to study drug 3.Patients in whom abdominal drain is in-situ 4.Patients who are unable to express VAS score accurately(mentally ill patients) 5.Patient refusal

Design outcomes

Primary

Measure	Time frame
To compare the duration of post operative analgesia offered by intraperitoneal Levobupivacaine alone or with dexmedetomidine in patients undergoing laparoscopic cholecystectomy and subsequent need of rescue analgesicTimepoint: until first rescue analgesia	—

Secondary

Measure	Time frame
Total rescue analgesic consumption and Post-operative adverse effects Timepoint: 24H	—

Countries

India

Contacts

Public ContactDr Suba L

Vinayaka Missions Medical College and Hospital, Karaikal

suba.cutiepie@gmail.com9578567506

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026