Comparartive Study To Determine Efficacy Of Buprenorphine Patch Versus Fentanyl Patch In Post Op Pain Relief In Lower Limb Surgeries

A Comparartive Study To Determine Efficacy Of Buprenorphine Patch Versus Fentanyl Patch In Post Op Pain Relief In Lower Limb Surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087035

Enrollment

110

Registered

2025-05-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 2: N00-N99- Diseases of the genitourinary system Health Condition 3: L00-L99- Diseases of the skin and subcutaneous tissue Health Condition 4: 7- Osteopathic Health Condition 5: O- Medical and Surgical

Interventions

Intervention1: Buprenorphine and Fentanyl patch: The patients will be randomly allocated in 2 groups of 55 patients in each. GROUP-B: Patients will be given transdermal buprenorphine patch

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients or legal attendant giving informed written consent for participation in the study 2.All patients posted for elective surgeries. 3.Age of the patient between 18-60 years. 4.BMI of the patient between 18.5-29.9kg/m2. 5.Patients belonging to ASA class I and II.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To compare post-operative pain relief between transdermal patches of buprenorphine and fentanyl patches in lower limb surgeries. Timepoint: 4hrs,8hrs,12hrs,16hrs,20hrs,24hrs,36,hrs,48hrs,60hrs,72hrs,84hrs,96hrs,108hrs,120hrs	—

Secondary

Measure	Time frame
1.To monitor hemodynamic stability (change in HR, SBP, DBP, SPO2) after application of buprenorphine and fentanyl patches. 2.To identify any adverse effect after the application of transdermal patches of buprenorphine and fentanyl in lower limb surgeries.Timepoint: 5 days	—

Countries

India

Contacts

Public ContactStuti Chamoli

Government Medical College,Haldwani

stutichamoli9@gmail.com7983969017

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026