A comparative study on recovery of muscle strength, measured using an instrument named Dynamometer, which gives strength of hand grip, after reversing anaesthesia induced muscle paralysis using two different drugs neostigmine and sugammadex in children undergoing surgery under general anaesthesia.

Comparison of dynamometer-based objective assessment of neuromuscular recovery after reversal with neostigmine Vs sugammadex in paediatric patients- a randomized triple-blinded study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087034

Enrollment

Registered

2025-05-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Neuromuscular block reversal with sugammadex: A single dose of 2mg/Kg of Sugammadex will be administered at the end of surgery for neuromuscular block reversal before extubation Control

Eligibility

Inclusion criteria

Inclusion criteria: Elective surgeries requiring neuromuscular blockade

Exclusion criteria

Exclusion criteria: Known neuromuscular disorders. History of allergy to study medications. Surgery involving upper limb. Fracture in dominant upper limb. Deformity in upper limb. Pre-existing pulmonary diseases. Elective mechanical ventilation in the post-operative period.

Design outcomes

Primary

Measure	Time frame
A comparison of post-extubation muscle strength using a hand-held force dynamometerTimepoint: Baseline (preoperative), 15, 30, 45,60 minutes after extubation in the postoperative period	—

Secondary

Measure	Time frame
A comparison of Post-operative PEFR with a peak expiratory flowmeter and Time to recovery to baseline muscle strength Timepoint: 15, 30, 45 and 60 minutes after extubation	—

Countries

India

Contacts

Public ContactA Chaitanya Pratyusha

All India Institute of Medical Sciences

chaitanyapa9@gmail.com9063571725

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026