The effect of isobaric Ropivacaine and isobaric Levobupivacaine with addition of Fentanyl in spinal anaesthesia for postoperative pain relief in patients posted for lower abdominal surgeries .

To compare the efficacy of isobaric Ropivacaine 0.75 percent with isobaric Levobupivacaine 0.5 percent in spinal anaesthesia with inj Fentanyl as an adjuvant in patients posted for lower abdominal surgeries . - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087028

Enrollment

Registered

2025-05-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K429- Umbilical hernia without obstruction or gangrene Health Condition 2: N433- Hydrocele, unspecified Health Condition 3: N47- Disorders of prepuce Health Condition 4: K37- Unspecified appendicitis Health Condition 5: N35- Urethral stricture Health Condition 6: K419- Unilateral femoral hernia, withoutobstruction or gangrene Health Condition 7: K458- Other specified abdominal hernia without obstruction or gangrene Health Condition 8: N759- Disease of Bartholins gland, unspec

Interventions

Intervention1: Intrathecal isobaric Levobupivacaine: Inj levobupivacaine 0.5 percent isobaric 3ml along with inj Fentanyl 25 micrograms 0.5ml will be given intrathecally to the patients undergoing low

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA I &II patients 2.Patients posted for elective lower abdominal surgeries under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Contraindication to subarachnoid block. 3.Central or peripheral neuropathies 4.Patients with bleeding disorders and those on anticoagulant therapy. 5.History of allergy to local anaesthetics. 6.Infection at site of block. 7.Obesity 8.Pregnant women. 9 Patients with psychiatric behaviour 10. History of chronic opioid use

Design outcomes

Primary

Measure	Time frame
Comparison of Duration of postoperative Analgesia between two groups isobaric levobupivacaine with fentanyl and isobaric ropivacaine with fentanylTimepoint: from the time of administration of study drug intrathecally to the patient complaint of pain postoperatively or VAS more than 3 postoperatively till 24 hours.	—

Secondary

Measure	Time frame
Comparision of hemodynamic stability between two groups isobaric ropivacaine with fentanyl and isobaric levobupivavaine with fentanylTimepoint: from the administration of drug in spinal till completion of surgery and postoperative till 24 hours;Comparision of adverse effects between two groups isobaric ropivacaine with fentanyl and isobaric levobupivavaine with fentanylTimepoint: from the administration of drug in spinal till completion of surgery and postoperative till 24 hours	—

Measure

Time frame

Comparision of hemodynamic stability between two groups isobaric ropivacaine with fentanyl and isobaric levobupivavaine with fentanylTimepoint: from the administration of drug in spinal till completion of surgery and postoperative till 24 hours;Comparision of adverse effects between two groups isobaric ropivacaine with fentanyl and isobaric levobupivavaine with fentanylTimepoint: from the administration of drug in spinal till completion of surgery and postoperative till 24 hours

—

Countries

India

Contacts

Public ContactMonika Varun Mittal

Smt Kashibai Navale Medical College And Hospital

monikatyagi1590@gmail.com9158224311

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026