To Evaluate The Dose Dependent Effects of Ibuprofen and Dexamethasone as Oral Premedication on the Success rate of Inferior Alveolar Nerve Block (IANB) in patients with Symptomatic Irreversible Pulpitis.

Efficacy Of Ibuprofen And Dexamethasone For Enhanced Success Of Inferior Alveolar Nerve Block In Irreversible Pulpitis: A Prospective, Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/087007

Enrollment

600

Registered

2025-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Ibuprofen: this group of patients will have ibuprofen 1 hr before the start of treatment Intervention2: Dexamethasone: this group of patient will have dexamethasone tablet 1hr prior to

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients experiencing moderate to severe pain and a prolonged response to pulp sensibility testing. 2. Should have a normal radiographic appearance. 3.Should not have taken any analgesics for at least 12 hours before. 4. Systemically healthy patients

Exclusion criteria

Exclusion criteria: 1. patients under 18 years old. 2. Patients with allergies and hypersensitivity to medications. 3. Pregnant or nursing women. 4. Immunocompromised patients. 5. Patients unable to give consent will be excluded from the study

Design outcomes

Primary

Measure	Time frame
pain assessmentTimepoint: pain assessment pre-operative, during access cavity, and during instrumentaion	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Sajid ali

Dr. Ziauddin Ahmad Dental College and Hospital

ashokoperative@yahoo.in9412732327

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026