Health Condition 1: O720- Third-stage hemorrhage
Conditions
Interventions
Intervention1: Administration of Calcium gluconate: Giving 1 gram (10ml) calcium gluconate intravenously over 10 minutes for high risk pregnant women
Control Intervention1: Normal saline: 10 ml of iso
Sponsors
JIPMER Intramural Research fund
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 years and more ASA 2 and 3 Gestational age more than 34 weeks Planned for c-section under spinal anesthesia Pregnant females with high risk for blood loss during c-section like previous cesarean section, twin pregnancy, severe obesity, history of previous postpartum hemorrhage
Exclusion criteria
Exclusion criteria: Pregnant females with heart disease, chronic renal disease, placenta accreta sprectum, pregnant females who are taking calcium channel blockers like nifedipine tablets
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of intravenous calcium gluconate with placebo on reduction of intrapartum blood loss in pregnant women posted for cesarean section with risk factor of postpartum hemorrhage.Timepoint: At the end of the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.verbal numerical rating scale of uterine tone 2.baseline & postoperative hemoglobin 3.baseline & post operative ionized calcium 4.total intraoperative intravenous fluids administered, total dose of vasopressors used & second line utero-tonic usedTimepoint: 1.Baseline, at 5 minutes, 10 minutes, 15 minutes after giving study drug 2. Baseline, at postoperative day 1 3.Baseline, at postoperative day 1 4.At the end of surgery | — |
Countries
India
Contacts
Public ContactDr Aswini kuberan
Jawaharlal Institute of Postgraduate Medical Education And Reserch
Outcome results
None listed