Treatment Of Gum Loss in Gum Disease Using Individuals Own Blood Derived Substances And Bone Graft Material.

Evaluation Of Clinical Efficacy of Concentrated Growth Factors-Enriched Bone Graft Matrix with Modified Laterally Repositioned Flap In The Management Of Isolated RT 2 Gingival Recession Defects Randomized Controlled Clinical Trial - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086989

Enrollment

Registered

2025-05-15

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K060- Gingival recession

Interventions

Intervention1: Control Group: Modified Laterally Repositioned Flap + sub epithelial connective tissue graft (SCTG) Intervention2: Test Group: Modified laterally repositioned flap + concentrated growth

Eligibility

Inclusion criteria

Inclusion criteria: Systemically healthy subjects with an age range of 18-60 years. Individuals diagnosed with recession defects in maxillary and mandibular anteriors (Cairo s RT2 or Miller s class III recession) Sites with a minimum depth of recession greater than or equal to 2mm. Isolated recession

Exclusion criteria

Exclusion criteria: Sites with probing pocket depth greater than or equal to 4mm. Teeth with mobility or associated with trauma from occlusion. Sites with dental caries and prosthetic restorations. Patients who exhibit unacceptable oral hygiene compliance during or after phase 1 therapy. Smokers. Pregnant and lactating women. Patients with known platelet disorders or using any medication that is known to interfere with platelet function. Patients with systemic conditions or disease influencing the course of periodontal disease and therapy

Design outcomes

Primary

Measure	Time frame
1.To assess and compare Mean root coverage from baseline to 6 months, within and between the treatment groups. 2.To assess and compare the percentage of Complete root coverage (CRC%) achieved at 6 months between the treatment groups Timepoint: 6 months	—

Secondary

Measure	Time frame
To evaluate and compare the following clinical outcomes measures from base line to 6 months. 1. Recession height (RH) between test and control group 2. Recession width (RW) between test and control group 3. Gingival phenotype (GP) between test and control group 4. Pedicle Flap thickness (GT) between test and control group 5. Probing pocket depth (PPD) between test and control group 6. Clinical attachment level (CAL) between test and control group 7. Keratinized tissue height (KTH) between test and control group 8. Width of attached gingiva (WAG) between test and control group 9. Relative vestibular depth (RVD) between test and control group Timepoint: 12 months	—

Measure

Time frame

To evaluate and compare the following clinical outcomes measures from base line to 6 months. 1. Recession height (RH) between test and control group 2. Recession width (RW) between test and control group 3. Gingival phenotype (GP) between test and control group 4. Pedicle Flap thickness (GT) between test and control group 5. Probing pocket depth (PPD) between test and control group 6. Clinical attachment level (CAL) between test and control group 7. Keratinized tissue height (KTH) between test and control group 8. Width of attached gingiva (WAG) between test and control group 9. Relative vestibular depth (RVD) between test and control group Timepoint: 12 months

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Countries

India

Contacts

Public ContactV Santhosh Devanadhan

SRM Dental College Ramapuram

drsandev@gmail.com8148877084

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026