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Effect Of Application Of The MINUTES Bundle Versus Existing Care On The Clinical Outcomes In The Initial Management Of Undifferentiated Circulatory Shock In The Emergency Department

Effect of application of the MINUTES bundle vs existing care on the clinical outcomes in the initial management of undifferentiated circulatory shock in the emergency department - a randomised control study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086987
Enrollment
100
Registered
2025-05-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R570- Cardiogenic shock Health Condition 2: R571- Hypovolemic shock Health Condition 3: R578- Other shock Health Condition 4: R652- Severe sepsis Health Condition 5: R579- Shock, unspecified

Interventions

Intervention1: MINUTES bundle: Application of MINUTES bundle components for the initial care of patients presenting with undifferentiated circulatory shock Control Intervention1: Standard care: the cu

Sponsors

Department of Emergency Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients presenting to the Emergency Department in undifferentiated circulatory shock, that is, with the following hemodynamic parameters - all the three criteria fulfilled 1. Systolic Blood Pressure less than 90 mm Hg 2. Mean Arterial Pressure less than 65 mm Hg 3. Shock Index (Heart Rate/Systolic Blood Pressure) more than or equal to 0.8

Exclusion criteria

Exclusion criteria: 1. Patients with age less than 18 years 2. Pregnant women 3. Patients presenting with trauma 4. Patients presenting in unresponsive state or in cardiac arrest 5. Patients whose initial management has been done in another hospital

Design outcomes

Primary

MeasureTime frame
To determine 7 days mortality in patients receiving care under MINUTES bundle versus patients receiving existing care for the initial management of undifferentiated circulatory shockTimepoint: 7 days—

Secondary

MeasureTime frame
To determine the time taken for the application of all and individual components of the MINUTES bundleTimepoint: To determine the time taken for the application of all and individual components of the MINUTES bundle;To compare between the 2 groups a. Lactate clearance at 2 hours, 6 hours b. Hemodynamic parameters - SBP, HR, MAP, SI at 2 hours, 6hours (Systolic Blood Pressure, Heart Rate, Mean Arterial Pressure, Shock Index) c. Length of hospital stay, ICU stay d. mortality upto 28 daysTimepoint: 2 hours, 6 hours, 28 days;To determine any possible complications or side effects associated with the application of the MINUTES bundleTimepoint:—

Countries

India

Contacts

Public ContactDr Mritunjay Kumar

All India Institue Of Medical Sciences New Delhi

dr.mritunjay@gmail.com9868023165

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026