None listed
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: Apparently healthy adults of both sexes.
Exclusion criteria
Exclusion criteria: 1. Subjects who are on B12 supplements. 2. Antibiotic use in the last 3 months. 3. Diarrhea in the last 3 months. 4. on special/fad diets. 5 History of gastrointestinal surgery ( bowel resection, gastrectomy, vagotomy, ileostomy, bariatric, colostomy) 6. Uncontrolled co-morbidities like diabetes hypertension and cardiovascular disease, or this with history of allergic or hypersensitive reaction, were excluded from the study. 7. Clinical suspicion of any of the vitamin B deficiencies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the first pass metabolism of instilled 13C B vitamins by measuring the difference in concentrations of the two different type of B vitamins being tracked.Timepoint: Only Baseline over a period of 4 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the total absorption of 13C labelled B vitamins from the colon, thereby develop a relationship between the concentrations of B vitamins observed in the systemic circulation & the actual amount absorbed in the colon of the subject.Timepoint: Only Baseline over a period of 4 hrs | — |
Countries
India
Contacts
Public ContactShalini Gajanan Hegde
St. Johns Medical College Hospital
Outcome results
None listed