Health Condition 1: O092- Supervision of pregnancy with other poor reproductive or obstetric history
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
PGIMER, Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Cases- Pregnant women between 20-24 weeks of gestation currently using a vaginal progesterone preparation (and have been using it for at least 4 weeks) for prevention of preterm birth due to prior spontaneous preterm birth or premature prelabour rupture of membranes. Controls- Healthy pregnant women between 20-24 weeks of gestation which include those women who are not using any vaginal progesterone preparation and have no history of prior preterm birth or preterm prelabour rupture of membranes.
Exclusion criteria
Exclusion criteria: 1.Women with cervical encerclage in situ 2.Multifetal pregnancy 3.Active infections like tuberculosis, HIV, genital herpes 4.Fetal malformations 5.Severe hypertension, uncontrolled diabetes, severe anemia, heart disease, autoimmune disorders or any other medical disorder 6.Antepartum haemorrhage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the vaginal lactobacilli species among pregnant women using vaginal progesterone for prevention of preterm birth and compare it with healthy pregnant women.Timepoint: 1.5 years | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the prevalence of vaginal infections (bacterial vaginosis, candidiasis and trichomonal vaginitis) among the above two groups of women.Timepoint: 1.5 years;To compare the chlamydial and gonococcal infections (assessed by urine PCR) among the two groups of women.Timepoint: 1.5 years;To see the various pregnancy outcomes (PTB) in the above two groups of women.Timepoint: 1.5 years | — |
Countries
India
Contacts
Public ContactDr Rashmi Bagga
Postgraduate Institute of Medical Education and Research, Chandigarh
Outcome results
None listed