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Comparative clinical and immunological analysis of open flap debridement versus closed debridement using Er:YAG laser in Stage III grade B generalized periodontitis: A randomised controlled clinical trial

Comparative clinical and immunological analysis of open flap debridement versus closed debridement using Er:YAG laser in Stage III grade B generalized periodontitis: A randomised controlled clinical trial - Open debridement versus closed debridement

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086938
Enrollment
20
Registered
2025-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Closed debridement of the arch with Er:YAG Laser 1 month after phase 1 periodontal therapy.: In the other half closed debridement with Er:YAG laser after 1 month of phase 1 periodonta

Sponsors

Army Dental Centre Research and Referral Dhaula Kuan, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with PPD equal to or greater than 5mm and equal to or less than 8mm in more than two non adjacent teeth affecting more than 30 percent of teeth.

Exclusion criteria

Exclusion criteria: 1. History of surgical and nonsurgical periodontal therapy in last 2yrs 2. Past or current tobacco users 3. Pregnant or Expecting or Lactating women 4. Full mouth bleeding score FMBS and Full mouth plaque score FMPS more than 10 percent after Phase I therapy 5. Patients who dont comply with the treatment protocol 6. Patients with co morbidities

Design outcomes

Primary

MeasureTime frame
1. Pocket probing depth 2. Clinical attachment level 3. Percentage of sites with bleeding on probing Timepoint: Baseline, 3 and 6months

Secondary

MeasureTime frame
TNF-alpha in GCFTimepoint: Baseline and 6 months

Countries

India

Contacts

Public ContactMaj Azhar Khan

Army Dental Centre Research and Referral

tprasanthavin@gmail.com8284851155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026