Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: nil: nil
Intervention2: Nil: Nil
Intervention3: patients will be given infusion of Injection Propofol 50 mcg /kg /min And
Dexmedetomidine 0.5mcg/kg/hr.: sedations will be started just p
Sponsors
Dr Aishwarya Hunashikatti
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA grade III fit patients. 2. Patients aged between 3 months and 12 years of age of either sex. 3. Patients undergoing cardiac surgeries for congenital heart disease and cardiopulmonary bypass. 4. Hemodynamically stable patients with all routine investigations within normal limits and without any comorbidities. 5. Written informed consent from the concerned patient.
Exclusion criteria
Exclusion criteria: 1. Patients who are not willing to participate in the study. 2. Patients with ASA grade IV and above physical status. 3. Patients who are aged less than 3 months and more than 12 years of age. 4. Patients who are posted for emergency procedures. 5. Patients with known allergy to the study drugs. 6. Patients who have facial and neck physical abnormalities that could make airway support difficult, respiratory diseases, severe myocardial depression, fever, chromosomal abnormalities, other multiple congenital anomalies or impairment of hepatic or renal function, endocrine dysfunction and epilepsy. 7. Patients weight less than 3 kgs 8. Cyanotic patients who have not undergone corrective procedure will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the Efficacy of ketamine and dexmedetomidine Vs propofol and dexmedetomidine for post operative sedation in pediatric cardiac surgical patients.Timepoint: a. To assess the Ramsay sedation score at 2,4,6,8,12,16 and 24 hours post operatively. b. To observe hemodynamic effects of both drugs. c. To observe any side effects. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the Efficacy of ketamine & dexmedetomidine Vs propofol and dexmedetomidine for post operative sedation in pediatric cardiac surgical patients.Timepoint: a. To access ease of weaning from ventilation & extubation while maintaing the airways. b. To check Arterial Blood Gas(ABG) analysis at initiation of ventilation in ICU, Every 8 th hourly, prior to extubation, Post 2 hour extubation & subsequently 8th hourly. | — |
Countries
India
Contacts
Public ContactDr Vipul K Sharma
Dr.D.Y.Patil Medical College,Hospital and Research Centre
Outcome results
None listed