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comparing effectiveness of Levetiracetam vs phenytoin as second line treatment in neonatal seizure

Levetiratcetam vs phenytoin as second line treatment in neonatal seizure - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086924
Enrollment
345
Registered
2025-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G800- Spastic quadriplegic cerebral palsy

Interventions

Intervention1: levetiracetam vs phenytoin in neonatal seizure: patient will be divided in two groups Group A will receive levetiractem Intervention2: levetiracetam vs phenytoin as second line drug in

Sponsors

Poonam uikey
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.both term and preterm neonates upto 28 days having seizures. 2.neonates who have reeived phenobarbitone as first line AED.

Exclusion criteria

Exclusion criteria: 1.Neonates with a positive history of maternal drug ingestion. 2.Neonates who received more than one anticonvulsant medication prior to enrollement. 3.Neonates with major congenital malforation

Design outcomes

Primary

MeasureTime frame
Short term outcome -death /discharge normal or abnormal HNNE at discharge Timepoint: at the time of discharge—

Secondary

MeasureTime frame
long term outcome prvalence of epilepsy,prevalence of cerebral palsy,prevalence of GDD using DASI, Normal or abnormal HINETimepoint: baselin 3 month—

Countries

India

Contacts

Public ContactDr. Shabd singh yadav

Shyam shah medical college rewa

Sshabd@yahoo.com9827260904

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026