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Comparison of two methods to arrest (stop) caries in milk teeth of children

Evaluation of success of nano silver fluoride modified versus silver diamine fluoride modified atraumatic restorative technique in primary molars a non-inferiority randomized control trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086881
Enrollment
288
Registered
2025-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K026- Dental caries on smooth surface

Interventions

Intervention1: Nano silver modified ART: Nano Silver Fluoride (NSF), a newer formulation containing silver nanoparticles, chitosan, and fluoride, offers a promising alternative. It exhibits strong ant

Sponsors

Abhishna P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Apparently healthy children in the age group 4-9 years. 2.Asymptomatic dentinal cavitated lesions accessible to hand instrumentation in at least one primary molar. 3.Children with Frankl behavior rating scale positive or definitely positive. 4.Children whose parents have consented to take part in the study and whose parents accept to report for the scheduled follow up

Exclusion criteria

Exclusion criteria: 1.Teeth with a history of pain in the tooth of interest, signs of pulpal and periapical pathology, such as having an abscess, fistula or sinus. 2.Children with developmental defects/hypoplasia in relation to the selected tooth. 3.Physiologic tooth mobility due to root resorption. 4.Children with known allergy to silver. 5.Children with designated molars having more than two surfaces involved with caries.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the success of atraumatic restorative technique on asymptomatic cavitated carious lesions in primary molars following pretreatment with either nano silver fluoride or silver diamine fluoride solution.Timepoint: 6 and 12 months

Secondary

MeasureTime frame
To evaluate & compare the degree of discolouration caused by the two atruamatic restorative techniques.Timepoint: 6 & 12 months;To compare & measure the parental satisfaction with the children s dental appearance after treatment with two restorative techniquesTimepoint: 6 & 12 months

Countries

India

Contacts

Public ContactAbhishna P

AIIMS,New Delhi

drkalpanabansal@gmail.com9810105132

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026