Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient aged between 18-65 years 2. Newly diagnosed cases of non-alcoholic fatty liver via transient elastography 3. Ability to give informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Any known secondary liver disease, including hepatitis B surface antigen or anti-hepatitis C virus antibodies. 2. Excessive alcohol consumption 3. Administration of medical treatment that may elevate alanine aminotransferase (ALT) or lead to hepatic steatosis (Drugs like amiodarone, risperidone, olanzapine, and valproic acid, etc). 4. Known diabetes and on multiple oral hypoglycaemic agents, or insulin. 5. Pregnant females, irrespective of gestational age. 6. Major chronic diseases including: renal, cardiovascular, lung, uncontrolled hypertension, inflammatory bowel disease, any malignancy and autoimmune disorders. 7. Orthopaedic contraindications for structured resistance training.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effectiveness of calorie-restricted diet combined with structured resistance training versus ad libitium physical activity on hepatic steatosis as assessed by Controlled Attenuation Parameter values in patients with non-alcoholic fatty liverTimepoint: BASELINE, 1MONTH, 3MONTH AND 6 MONTHS | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in Anthropometric, Body composition, Cardiometabolic, Biochemical parameters and hand grip strength among both the groupsTimepoint: BASELINE, 1MONTH, 3MONTH AND 6 MONTHS | — |
Countries
India
Contacts
Institute of Liver and Biliary Sciences