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Corelation of pesticides with hypothyroidism in children

Association between Transfluthrin and its metabolites with idiopathic hypothyroidism in children - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/05/086819
Enrollment
30
Registered
2025-05-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E038- Other specified hypothyroidism

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Department of Biochemistry
Lead Sponsor
Department of Biochemistry
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Subjects presented with diagnosed idiopathic hypothyroidism

Exclusion criteria

Exclusion criteria: Congenital hypothyroidism Structural thyroid anomalies

Design outcomes

Primary

MeasureTime frame
Corelation of transfluthrin and its metabolite in children diagnosed with idiopathic hypothyroidismTimepoint: Subject enrollment 2 months Sample processing 2 weeks Data Analysis 2 weeks Data presentation 1 week—

Secondary

MeasureTime frame
Effect of transfluthrin exposure in TR-alpha1, TR-beta1, TSHR, SLC5A5(NIS), TPO expression on Nthy-ori 3-1 thyroid cell line.Timepoint: Cell Line maintenance 3 weeks Treatment of Transfluthrin 2 weeks RNA extraction for PCR 1 week—

Countries

India

Contacts

Public ContactAAKRITI GUPTA

Maulana Azad Medical College

binita.dr@gmail.com9810592004

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026