Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Group O: Intravenous ondansetron 4mg, 5 minutes before spinal anaesthesia in parturients undergoing elective LSCS
Control Intervention1: Group G: Intravenous Granisetron 3mg, 5 minutes
Sponsors
Sushma
Eligibility
Inclusion criteria
Inclusion criteria: Parturients belonging to ASA grade 1 and 2 with more than 36 weeks gestation undergoing elective LSCS for a singleton pregnancy with Height 150 - 170cm.
Exclusion criteria
Exclusion criteria: Patient refusal Parturients with spinal deformity Parturients with medical and obstretric complications like anemia, cardiac disease, gestational hypertension, gestational diabetes, shock, liver disorders, septicemia and hypertension. Known hypersensitivity to local anaesthetics and study drugs. Subjects having any absolute or relative contraindications for spinal anaesthesia like raised intracranial pressure, severe hypovolemia, bleeding diathesis and local infection. Parturients with BMI more than 30 On drugs like selective serotonin reuptake inhibitors and migraine medications. Intraoperative blood loss more than1 litre
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of hemodynamic parameters like systolic blood pressure and heart rateTimepoint: 2,4,6,8,10,15,20,25,30,35,40,50,60,70,80,90 minutes and till 3 hours postoperative period | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess total requirement of intravenous ephedrine to treat hypotension and to assess intravenous atropine to treat bradycardia to assess incidence of nausea vomiting and intra operative and post operative shiveringTimepoint: 2,4,6,8,10,15,20,25,30,35,40,50,60,70,80,90 minutes and till 3 hours postoperative period | — |
Countries
India
Contacts
Public ContactDr B C Vijayalakshmi
Mysore medical college and research institute, mysuru
Outcome results
None listed