Comparison of 4ml of 1 percent lignocaine with 2ml of 2 percent lignocaine for superior laryngeal nerve block during awake fibreoptic intubation

Comparison of 4 ml of 1 percent lignocaine versus 2ml of 2 percent lignocaine for landmark guided superior laryngeal nerve block to aid awake fibre-optic intubation - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086771

Enrollment

Registered

2025-05-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Drug - 1% Lignocaine: Landmark guided single shot superior laryngeal nerve block with 4ml of 1% Lignocaine Control Intervention1: Drug - 2% Lignocaine: Landmark guided single shot super

Eligibility

Inclusion criteria

Inclusion criteria: - American society of anaesthesiologists physical status 1 and 2 - Patients requiring Awake Fibre-optic bronchoscopy guided nasotracheal intubation

Exclusion criteria

Exclusion criteria: - Haemodynamically unstable patients - Coagulopathy - Restricted neck extension - Allery to study drug - Front of neck masses - Making identification of anatomical landmarks difficult - Known epileptic patients - Pregnant women - Patients with psychiatric problems

Design outcomes

Primary

Measure	Time frame
To measure degree of vocal cord adduction in both group of patients while manuoevring through FOB through glottis .Timepoint: During intubation (Intra-operative period)	—

Secondary

Measure	Time frame
1. To measure the time required for intubation (from entry into nostrils to first appearance of ETCO2 trace) 2. To measure the requirement of supplemental lignocaine SAYGO (1 ml aliquots) 3. Hemodynamic parameters (heart rate & MAP from the start till 5 minutes after intubation) 4. Patient perception ofdiscomfort during the procedure (No/mild/severe discomfort) - It will be assessed postoperatively (24 hours after extubation) by asking the patient.Timepoint: 1 minute, 3 minute, 6 minute, 9 minute, 10 minute	—

Measure

Time frame

1. To measure the time required for intubation (from entry into nostrils to first appearance of ETCO2 trace) 2. To measure the requirement of supplemental lignocaine SAYGO (1 ml aliquots) 3. Hemodynamic parameters (heart rate & MAP from the start till 5 minutes after intubation) 4. Patient perception ofdiscomfort during the procedure (No/mild/severe discomfort) - It will be assessed postoperatively (24 hours after extubation) by asking the patient.Timepoint: 1 minute, 3 minute, 6 minute, 9 minute, 10 minute

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Countries

India

Contacts

Public ContactDr Harish Kumar

All India Institute of Medical Sciences, Bhopal

harishcmckol@gmail.com94713 00943

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026