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Comparison Of BIS Guided Total intravenous Anaesthesia (TIVA) V/S Inhaled Anaesthesia: A Prospective Randomized Clinical Study

Comparison Of Bispectral index (BIS) guided opioids free Total intravenous anaesthesia(TIVA) v/s Inhaled Anaesthesia in supratentorial craniotomy: A Randomized Clinical Study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086721
Enrollment
90
Registered
2025-05-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S069- Unspecified intracranial injury Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Total intravnous anaesthesia: Inj MAGNESIUM SULFATE 40 mg/kg and inj DEXMEDETOMIDINE 1 microgram/kg in 100 ml NS before 15 mins of inductions and for Maintanence we give inj PROPOFOL I

Sponsors

Government Medical College Vadodara
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 2/3. Malampatti Grade 1/ 2/3 Duration of surgery less than 5 hours Patient able to give written & informed consent. Glasgow Coma Scale 15/15 undergoing elective supratentorial surgery

Exclusion criteria

Exclusion criteria: Patient not willing for procedure. Patient with scalp infection Patients having uncontrolled Diabetes, Hypertension, Liver and Kidney disorders. Pregnant patients. Hypersensitivity to any local anesthetic drug or drugs used in this study. Patients with significant h/o drug or alcohol abuse, psychiatric illness Patient on b blocker and calcium channel blocker Patients with history of neurological/ cognitive deficits, myopathy, mental disability Patients with a significant history of brain tumor greater than 30mm in any dimension

Design outcomes

Primary

MeasureTime frame
Haemodynamic StabilityTimepoint: AT 10 minutes AT 15 minutes AT 30 minutes AT 1 HOUR AT 2 HOUR

Secondary

MeasureTime frame
Extubation TIme and Recovery Profile using Fast Track CriteriaTimepoint: Till 24 hours

Countries

India

Contacts

Public ContactDr Kumud Ganvit

Government Medical College, vadodara

drkumudsganvit@gmail.com9825607625

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026