Impact of Oxygen Levels on Lung function During Laparoscopic Surgery

Determining the effect of fraction of inspired oxygen during alveolar recruitment on absorption atelectasis in laproscopic surgery using lung ultrasound score: A one year randomised clinical study. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086661

Enrollment

Registered

2025-05-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified Health Condition 2: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Interventions

Intervention1: fraction of inspired oxygen 40%: After setting the FIO2 (40%) according to the assignment, continuous positive airway pressure will be applied from 20 cmH2O in 5- cmH2O stepwise increme

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patient with healthy, no respiratory symptoms, no pre-existing lung pathologies (negative CXR) 2) Age between 18-60 years 3) BMI more than 35 kg/m2 4) ASA I & II 5) Elective laproscopic surgeries in trendelenberg position.

Exclusion criteria

Exclusion criteria: ASA grade III & IV Patient with pulmonary, cardiac and neuromuscular diseases. Corresponding thorasic surgical history and respiratory tract infection were excluded. Those undergoing conversion from laproscopic to open surgery. Those experiencing critical postoperative complication such as severe subcutaneous emphysema and peunmothorax.

Design outcomes

Primary

Measure	Time frame
To compare the incidence of atelectasis in patients undergoing laproscopic surgery under general anaesthesia receiving lung recruitement maneuver with two different Fio2 concentration of 0.4 and 1.0 .Timepoint: To compare the incidence of atelectasis in patients undergoing laproscopic surgery under general anaesthesia receiving lung recruitement maneuver with two different Fio2 concentration of 0.4 and 1.0 .	—

Measure

Time frame

To compare the incidence of atelectasis in patients undergoing laproscopic surgery under general anaesthesia receiving lung recruitement maneuver with two different Fio2 concentration of 0.4 and 1.0 .Timepoint: To compare the incidence of atelectasis in patients undergoing laproscopic surgery under general anaesthesia receiving lung recruitement maneuver with two different Fio2 concentration of 0.4 and 1.0 .

—

Secondary

Measure	Time frame
To compare the post operative pulmonary complications.Timepoint: preoperatively and postoperatively	—

Countries

India

Contacts

Public ContactTejesh S

Jawaharlal Nehru Medical College

drchaitanya12@gmail.com8150038305

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026