To check level of pain in children aged between 6-12 years using 2 percent Lignocaine gel and Acmella oleracea gel while giving intraoral injection for treatment

Comparative evaluation of pain perception following topical application of 2 percent Lignocaine gel and Acmella oleracea gel prior to intraoral injection in children aged 6-12 years - in vivo study - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086624

Enrollment

Registered

2025-05-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K04- Diseases of pulp and periapical tissues Health Condition 2: K01- Embedded and impacted teeth

Interventions

Intervention1: Acmella oleracea gel: Herbal topical anesthetic gel will be used in patients for study in span of 2 years Control Intervention1: Lignocaine gel: 2 percent lignocaine gel will be used in

Eligibility

Inclusion criteria

Inclusion criteria: Children who visit department for pulpotomy, pulpectomy and extraction Children with Frankl behavior rating 2,3 and 4 Patient who require bilateral infiltration or bilateral nerve block local anesthesia for dental treatment

Exclusion criteria

Exclusion criteria: Children with any systemic disease,acute infection Mentally retarded children Patient under sedative drugs Patient who are allergic to local anesthesia Patient with restricted mouth opening

Design outcomes

Primary

Measure	Time frame
The acmella oleracea gel will show more effectiveness in reducing pain perception than 2 percent lignocaine gel prior to intraoral injection in children aged 6-12 yearsTimepoint: Baseline	—

Secondary

Measure	Time frame
There will be no significant difference between acmella oleracea gel and 2 percent lignocaine gel in reducing pain perception prior to intraoral injection in children aged 6-12 yearsTimepoint: baseline	—

Countries

India

Contacts

Public ContactDr Sherin Meriya Williams

Maharishi Markandeshwar (Deemed to be University) college of Dental Sciences and Research

priyankasharma25989@gmail.com9416068601

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026