Comparison of efficacy of Preoxygenation which is done before intubation with face mask along with apnoeic oxygenation with nasal cannula versus face mask alone which is standard method in patients undergoing intubation in emergency: A randomized control trial.

Comparison of efficacy of Preoxygenation standard face mask along with apnoeic oxygenation with nasal cannula versus face mask alone in patients undergoing intubation in emergency: A randomized control trial. - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086604

Enrollment

618

Registered

2025-05-09

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: pre oxygenation with bag and mask along with nasal cannula: pre oxygenation for 3 minutes will be done with bag and mask along with apnoeic oxygenation ( oxygen flow of 15 L/min) will c

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria includes patient coming to emergency department age more than 18, requiring intubation and willing to take part in trial.

Exclusion criteria

Exclusion criteria: 1. Patient in cardiac arrest 2. Pregnant and breast feeding 3. Already receiving positive pressure ventilation 4. Patient requiring delayed sequence intubation 5. Patient requiring video or fibre optic intubation

Design outcomes

Primary

Measure	Time frame
lowest oxygen saturation during the interval between induction of anaesthesia till 2 minutes after tracheal intubationTimepoint: the interval between induction of anaesthesia before intubation till 2 minutes after the procedure of intubation is completed.	—

Secondary

Measure	Time frame
hypoxemia during intubation i.e. oxygen saturation of less than 90 %.Timepoint: Interval from induction of anaesthesia till 2 minutes after tracheal intubation;Severe hypoxemia during intubation i.e. oxygen saturation of less than 80%.Timepoint: Interval from induction of anaesthesia till 2 minutes after tracheal intubation.;Change in oxygen saturationTimepoint: Recorded before pre oxygenation & after 3 minutes of pre oxygenation.;hypoxemia post intubation i.e. oxygen saturation of less than 90%.Timepoint: During the interval from 2 to 15 minutes after tracheal intubation	—

Measure

Time frame

hypoxemia during intubation i.e. oxygen saturation of less than 90 %.Timepoint: Interval from induction of anaesthesia till 2 minutes after tracheal intubation;Severe hypoxemia during intubation i.e. oxygen saturation of less than 80%.Timepoint: Interval from induction of anaesthesia till 2 minutes after tracheal intubation.;Change in oxygen saturationTimepoint: Recorded before pre oxygenation & after 3 minutes of pre oxygenation.;hypoxemia post intubation i.e. oxygen saturation of less than 90%.Timepoint: During the interval from 2 to 15 minutes after tracheal intubation

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Countries

India

Contacts

Public ContactDr Parampreet singh

AIIMS, Rishikesh

poonam.em@aiimsrishikesh.edu.in8477987835

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026