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To study the effect of yoga-based breathing and relaxation regimen on preoperative anxiety and stress biomarkers in patients undergoing neurosurgery

Effect of yoga-based breathing and relaxation regimen on preoperative anxiety and neurological biomarkers in neurosurgical patients: A prospective randomized controlled trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086577
Enrollment
80
Registered
2025-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C71- Malignant neoplasm of brain

Interventions

Intervention1: Group Y (Yogic breathing): Patients in this group will receive yoga-based breathing and relaxation regimes for 5 days before undergoing elective supratentorial glioma excision. Control

Sponsors

Sanjay Gandhi Postgraduate Institute of Medical Sciences SGPGIMS Lucknow
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I or II adult patients (aged 18-65 years) of either sex 2. Conscious patients who are oriented to time, place, and person with GCS 15/15 scheduled for elective craniotomy and excision of supratentorial tumors under general anesthesia

Exclusion criteria

Exclusion criteria: 1. Patient/patient attendants unwilling to give consent 2. Patients experiencing significant mass effect such as headache, nausea, vomiting, photophobia, drowsiness, or any other signs of raised intracranial pressure 3. Patients with motor sensory deficit 4. Patients with hearing or vision impairment 5. Patients with tumor-induced seizures who are uncontrolled on weight-appropriate antiepileptic medication 6. Severe pulmonary disorders i.e., restrictive or obstructive lung disease 7. Severe coronary artery disease or heart failure 8. Smoking or alcohol abuse 9. Psychiatric disorder 10. Emergency surgery 11. Patients with recurrent tumors for re-do surgery 12. Patients with significant skeletal or joint disorders hindering them from performing the relevant yoga postures/ techniques

Design outcomes

Primary

MeasureTime frame
To determine the effect of a short-term yoga-based breathing regimen on preoperative anxiety, using the State-Trait Anxiety Inventory (STAI)Timepoint: Before surgery—

Secondary

MeasureTime frame
1. To evaluate the impact of yoga-based breathing & relaxation practices, continued into the postoperative period, on serum biomarkers including GFAP (Glial Fibrillary Acidic Protein), NfL (Neurofilament Light), S100beta, & BDNF (Brain Derived Neurotropic Factor) at 6 weeks. 2. To explore the feasibility & adherence of supervised tele-yoga sessions in the perioperative care of neurosurgical patients.Timepoint: 6 weeks—

Countries

India

Contacts

Public ContactDr Nidhi Singh

Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow

nidhisingh22@gmail.com9501522330

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026