Health Condition 1: M270- Developmental disorders of jaws
Conditions
Interventions
Intervention1: Study group: ERAS -MaxFac Protocol: ERAS MaxFac Protocol. Complex carbohydrate drink 2 hours prior to surgery.
Intraoperative 0.2% Ropivacaine.
Lipus Regimen Followed Post operatively.
Sponsors
Jasnoor Singh Sidhu
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 - 50 years. Patients reporting for management of trauma involving maxilla and mandible. Patients reporting for management of developmental deformities involving maxilla and mandible. Patients categorized under ASA I or II. Patients reporting with Mallampati Score of I/II.
Exclusion criteria
Exclusion criteria: Patients less than 18 years and greater than 50 years. Patients categorized under ASA status III and IV. Patients with uncontrolled systemic diseases or concomitant head injuries, long bone injury, C- spine injury. Patients presenting with psychiatric illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Stress by a) Biochemical evaluation of Serum Cortisol b) By Zung Self-Rating Anxiety Scale (SAS). 2.Bone Healing by a) Biochemical evaluation of Serum Osteocalcin, b) By radiological evaluation of CT-Bone Mineral Density. 3.Quality of life by WHOQOL-BREF. 4.Muscle Mass by Ultrasound, thickness of masseter in mm. 5.Pain by Visual analogue scale(VAS). 6.Blood Glucose by Capillary blood glucose Timepoint: 1.a) Serum Cortisol:Pre-op, Post-op (10:00 am, daily 7 days) b) Zung SAS: Pre-op, Post-op daily 7 days (1st week), once weekly 7 weeks. 2.a) Serum Osteocalcin:Pre-op, Post-op (8th week).b) CT-BMD: Pre-op,Post-op (8th week). 3.WHOQOL-BREF:Pre-op, post-op daily 7 days (1st week), once weekly 7 weeks. 4.Masseter thickness (USG):Pre-op, Post-op (8th week). 5.VAS:Post-op daily 7 days, once weekly 7 weeks. 6.CBG:Pre-op (3 times 6hrly), post-op (2 days, 6hrly), Day 3 7 (once daily). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Inflammation by serum IL6 2. Surgical site infection by Southampton Wound Score. 3. Aspiration present or not at Intra-op during intubation/extubation. 4. Post operative nausea & vomiting by Apfel Risk Score 5. Functional recovery by mouth opening Timepoint: 1. IL-6: Pre-op, Post-op (Days 1, 3, 5). 2. Southampton Wound Score: Post-op daily 7 days, once weekly 7 weeks. 3. Aspiration: Intra-op (intubation/extubation), Post-op Day 1, 2. 4. Apfel Score (PONV): Post-op Day 0, 1, 2. 5. Mouth Opening: Pre-op, Post-op Weeks 1 6(once weekly). | — |
Countries
India
Contacts
Public ContactDr Elavenil Panneerselvam
SRM Dental College, Ramapuram, Bharathi Salai, Chennai 600089, Tamil Nadu, India
Outcome results
None listed