Health Condition 1: O80-O82- Encounter for delivery Health Condition 2: O80-O82- Encounter for delivery
Conditions
Interventions
Intervention1: Curcumin Drug Group: Drug: Curcumin (C3 Complex 525 mg) + Piperine (Bioperine 2.5 mg)
Dose Schedule:
First dose: Night before surgery (oral)
Second dose: Morning of surgery (2-4 hours
Sponsors
Maharani Laxmi Bai Medical College Jhansi
Eligibility
Inclusion criteria
Inclusion criteria: Undergoing elective cesarean section ASA physical status II or III Willing to give written informed consent
Exclusion criteria
Exclusion criteria: Pregnancy-induced hypertension (PIH) Gestational or preexisting diabetes mellitus Allergy to curcumin or piperine Chronic analgesic or steroid use Known bleeding or clotting disorder Autoimmune or chronic inflammatory disorders Active infection or clinical sepsis at time of enrollment Planned or proposed vertical skin incision for cesarean delivery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 Change in inflammatory markers (IL-6, CRP, D-dimer) at baseline, 24h, and 72h post-op 2 Total postoperative analgesic requirement in the first 24h to maintain VAS less than 3 3 Wound healing score using the REEDA scale on postoperative Day 3 and Day 7 Timepoint: 24 hours , 72 hours , day 3 and day 7 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Total analgesic consumption over 72 hours 2 Pain Scores (VAS at 6h, 12h, 24h, 48h, & 72h) 3 Fatigue scores using 10-point interval rating scale (IRS) at 24h, 48h, Day 7 4 Maternal satisfaction using a 5-point Likert scale 5 Postoperative complications (e.g., fever, infection, delayed mobilization) 6 Length of hospital stay 7 Neonatal outcome assessed using Apgar scores at 1 & 5 minutes after delivery Timepoint: 6 hours , 12 hours, 24 hours , 48 hours, 72 hours, day 7 | — |
Countries
India
Contacts
Public ContactAnshul Jain
M.L.B MEDICAL COLLEGE
Outcome results
None listed