Health Condition 1: E46- Unspecified protein-calorie malnutrition
Conditions
Interventions
Intervention1: Early Feed Fortification (EFF): Early feed fortification at feed volume of 40ml/kg/day with bovine based human milk fortifier (HMF) added to Mothers Own Milk (MOM). 1g HMF powder will b
Sponsors
IMS and SUM Hospital SOA University
Eligibility
Inclusion criteria
Inclusion criteria: All babies born less than 1500g birth weight and on incremental feeding up to 40ml/kg/day.
Exclusion criteria
Exclusion criteria: Major congenital abnormality (including known chromosomal abnormality), Major GI anomalies requiring surgery, Hemodynamic instability as defined by the need for more than one inotropic support prior to randomization, Antenatal Doppler changes such as Absent End Diastolic Flow/Reversal of End Diastolic Flow and babies born outside our hospital and admitted beyond 48hrs of life.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess, between EFF and SFF groups, for weight gain velocity in g/kg/day.Timepoint: At discharge from hospital | — |
Secondary
| Measure | Time frame |
|---|---|
| Length and head circumference gain and velocityTimepoint: At discharge;Weight, head circumference and length gain and velocitiesTimepoint: At 4 weeks and 3 months post natal age;Time to reach full feeds (150ml/kg/day)Timepoint: ;Time to regain birth weightTimepoint: ;Episodes of feeding intolerance with NPO in hoursTimepoint: At discharge;Weight, length and head circumference growth velocityTimepoint: Weekly till 4 weeks post natal age;NEC stage 2 & beyondTimepoint: At discharge or death;Incidence of extrauterine growth restrictionTimepoint: At discharge;Duration of parenteral nutritionTimepoint: At discharge;Culture positive sepsisTimepoint: At discharge;Duration of Hospital stay (in days)Timepoint: At discharge;All cause mortalityTimepoint: | — |
Countries
India
Contacts
Public ContactDr Neha Goudar
IMS and SUM Hospital (SOA University)
Outcome results
None listed