Health Condition 1: H160- Corneal ulcer
Conditions
Interventions
Intervention1: Antibiotic Therapy: Cephazoline and Ciprofloxin combination vs Tobramycin.
Follow-up visits: 3 days, 1 week, 2 weeks, 4 weeks, 6 weeks, 2 months, and 3 months.
Control Intervention1: An
Sponsors
L V Prasad Eye Institute
Eligibility
Inclusion criteria
Inclusion criteria: 1.Microbiologically confirmed bacterial keratitis smear or smear negative cases where the the fungus has been ruled out by microscopic examination. 2.No prior study medication use exceeding six times per day for more than 10 days. 3.Corneal infiltrate size 4 6 mm, with stromal involvement not exceeding two-thirds of corneal thickness. 4.Vision in the other eye better than 20/200. 5.Willingness to participate in the study. 6.Non-pregnant individuals. 7.Systemically stable patients. 8.Willingness for admission or regular follow-up.
Exclusion criteria
Exclusion criteria: 1.Mixed infection 2.Participant not willing to participate 3.Having Advanced form of infection 4.Limbal involvement 5.Scleral involvement 6.Posterior chamber involvement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Number of cases achieving medical cure. 2.Incidence of corneal perforations. 3.Number of patients requiring urgent TPK. Timepoint: Follow-up visits: 3 days, 1 week, 2 weeks, 4 weeks, 6 weeks, 2 months, and 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| Best spectacle-corrected visual acuity (BSCVA) at 3 months.Timepoint: 3 months | — |
Countries
India
Contacts
Public ContactDrBhupesh Bagga
L V Prasad Eye Institute
Outcome results
None listed