Study on Gum Healing in Adults with Bone Loss Around Teeth Using Two Types of Flap Surgery and Hyaluronic Acid Gel

Evaluation Of Soft Tissue Healing In Intrabony Defects Using Single Flap Approach And Non-Incised Papilla Surgical Approach In Conjunction With Hyaluronic Acid - A Randomized Controlled Clinical Study . - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086450

Enrollment

Registered

2025-05-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Group 3 Single-flap approach with Hyaluronic Acid. Group 4 Non-incised surgical approach with Hyaluronic Acid.: To evaluate Wound Healing(WH) Gingival Recession(RCE)Clinical Attachment

Eligibility

Inclusion criteria

Inclusion criteria: 1 Sites with intrabony defects and persisting pockets, probing depth more than 6mm and bleeding on probing (BOP) at re-evaluation 6 weeks after non-surgical periodontal therapy. 2 Radiographic intrabony component more than 3mm. 3 Limited to no extension of the defect on the lingual or palatal side as assessed by preoperative bone sounding. 4 Full mouth plaque score (FMPS) and full mouth bleeding score (FMBS) less than 20% before surgery.

Exclusion criteria

Exclusion criteria: 1 Pregnant or lactating women. 2 Tobacco, Smoking. 3 Untreated periodontal conditions. 4 Any condition associated with poor compliance or failure to maintain good oral hygiene. 5 Acute infectious lesions in areas intended for surgery. 6 Teeth with grade II or higher mobility. 7 Restorations or carious lesions on root surfaces that are associated with the intrabony defect.

Design outcomes

Primary

Measure	Time frame
To evaluate the change in Wound healing, Gingival Recession Clinical attachment levelTimepoint: 1 Wound healing (WH)- Recorded using Landry Healing index (HI), after periodontal surgery at baseline, 3 months. 2 Gingival recession (REC) Measured using lower border of customized occlusal stent to the crest of the gingival margin using UNC-15 Periodontal probeat baseline, 3 months. 3 Clinical attachment level (CAL) -Measured using the lower border of customized occlusal stent to the height of the papilla using same UNC-15 Periodontal probeat baseline, 3 months.	—

Measure

Time frame

To evaluate the change in Wound healing, Gingival Recession Clinical attachment levelTimepoint: 1 Wound healing (WH)- Recorded using Landry Healing index (HI), after periodontal surgery at baseline, 3 months. 2 Gingival recession (REC) Measured using lower border of customized occlusal stent to the crest of the gingival margin using UNC-15 Periodontal probeat baseline, 3 months. 3 Clinical attachment level (CAL) -Measured using the lower border of customized occlusal stent to the height of the papilla using same UNC-15 Periodontal probeat baseline, 3 months.

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Secondary

Measure	Time frame
To evaluate the measures outlined were changes in Probing depth, Bleeding on probing, Intrabony defects.Timepoint: 1 Pocket Depth (PPD) - Measured using lower border of customized occlusal stent from gingival margin to base of the pocket using UNC-15 - Periodontal probe at baseline, 3 months. 2 Intrabony defect fill: will be assessed at baseline, 3 months with standard IOPA. 3 Full mouth bleeding score (FMBS)- will be assessed by sulcus bleeding index -Muhlemann H.R.and Son at baseline, 3 months.	—

Measure

Time frame

To evaluate the measures outlined were changes in Probing depth, Bleeding on probing, Intrabony defects.Timepoint: 1 Pocket Depth (PPD) - Measured using lower border of customized occlusal stent from gingival margin to base of the pocket using UNC-15 - Periodontal probe at baseline, 3 months. 2 Intrabony defect fill: will be assessed at baseline, 3 months with standard IOPA. 3 Full mouth bleeding score (FMBS)- will be assessed by sulcus bleeding index -Muhlemann H.R.and Son at baseline, 3 months.

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Countries

India

Contacts

Public ContactDrGogulamudi Shiny

Kamineni Institute of Dental Sciences

drjagadishreddy@gmail.com9542479919

Outcome results