Using Low Level Laser Therapy to Reduce Pain After Root Canal Retreatment: A Randomized Study

The effect of photobiomodulation therapy on postoperative pain after endodontic retreatment -A Randomized control study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086434

Enrollment

Registered

2025-05-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: A488- Other specified bacterial diseases

Interventions

Intervention1: Diode laser ( Biolase Epic X ): LLLT group (Group B) will be irradiation using a BioDiode laser in the first appointment following re-rct steps. Diode laser exposure ( Biolase Epic X )

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients will report their preoperative pain on 10 cm Visual Analog Scale (VAS) with Tenderness on percussion pain VAS less than 50. 2. Mandibular and mandibular molars with periapical lesion with Orstavik periapical index classification with score of 2 or 3 will be chosen that require Re Root Canal Treatment. 3. Patients in good health, as determined by their medical history and responses to verbal questioning, will be included in this study. 4. Patients who have given informed consent will be included in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with periodontal probing greater than 3 mm 2. Patients with swelling or sinus tract 3. Patients with any medical condition 4. Patients who took medications (Eg: analgesics) that could modify the pain assessment 12 hours before the first visit.

Design outcomes

Primary

Measure	Time frame
to evaluate the effect of photobiomodulation therapy on postoperative pain following endodontic retreatment.Timepoint: Post operative pain assessment will be carried out at 8hrs, 24 hrs, 48 hrs and 7th day after the patient s first visit using Visual Analog Scale (VAS) scale.	—

Secondary

Measure	Time frame
To compare the efficiency of Photo Biomodulation Therapy & conventional management in reducing postoperative pain in Re-RCT cases.Timepoint: Post operative pain assessment for both the groups will be carried out at 8hrs, 24 hrs, 48 hrs & 7th day after the patients first visit using Visual Analog Scale.;To compare the effectiveness of Photobiomidulation therapy on maxillary & mandibular archesTimepoint: Post operative pain assessment will be carried out at 8hrs, 24 hrs, 48 hrs & 7th day after the patients first visit.	—

Measure

Time frame

To compare the efficiency of Photo Biomodulation Therapy & conventional management in reducing postoperative pain in Re-RCT cases.Timepoint: Post operative pain assessment for both the groups will be carried out at 8hrs, 24 hrs, 48 hrs & 7th day after the patients first visit using Visual Analog Scale.;To compare the effectiveness of Photobiomidulation therapy on maxillary & mandibular archesTimepoint: Post operative pain assessment will be carried out at 8hrs, 24 hrs, 48 hrs & 7th day after the patients first visit.

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Countries

India

Contacts

Public ContactJasleen Kaur

Shree Guru Gobind Singh Tricentenary University

as.ankita06@gmail.com9682575180

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026