Studying root damage of tooth during braces treatment in patients with split lips and palate using 3 dimensional facial scans and biological markers from gingival fluid during different time periods of treatment

Evaluation of Root Resorption in Unilateral Cleft Lip and Palate Patients using 3-Dimentional Radiography and Resorption Markers - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086417

Enrollment

Registered

2025-05-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q375- Cleft hard and soft palate with unilateral cleft lip

Interventions

Intervention1: fixed orthodontic treatment: Patients with unilateral cleft lip and palate will be treated with fixed orthodontic treatment and root resorption assessed with CBCT before and after the t

Eligibility

Inclusion criteria

Inclusion criteria: Surgically repaired Unilateral Cleft Lip and Palate patients with GOSLON Yardstick groups 1,2 and 3. Age group between 14 to 30 years Systemically healthy patients. Patient has not undergone any orthodontic treatment in the past 3 months

Exclusion criteria

Exclusion criteria: Syndromic Unilateral Cleft Lip and Palate patients. Patients with Bilateral Cleft Lip and Palate Patient s requiring orthognathic surgery. Patients with signs and symptoms of any bone disorders

Design outcomes

Primary

Measure	Time frame
To do a 3D volumetric assessment of root resorption in the Cleft side and non cleft side of the maxillary and mandibular arches in Unilateral Cleft Lip and Palate (UCLP) patients after fixed orthodontic treatment using Cone Beam Computed Tomography (CBCT) . Timepoint: T0-Before treatment T1-After treatment	—

Secondary

Measure	Time frame
To evaluate the levels of biomarkers dentin sialoprotein (DSP) and dentin phosphoprotein (DPP), in UCLP patients undergoing fixed orthodontic treatment.Timepoint: T0-Before treatment T1-3 weeks of treatment T2- 12 weeks of treatment T3- 6 months of treatment	—

Countries

India

Contacts

Public ContactDr Anjali Chinmayan

Manav Rachna Dental College

drpuneetbatra@gmail.com9810335961

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026