Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with chronic plague psoriasis Patients with plague psoriasis involving more than 10 percent body surface area.
Exclusion criteria
Exclusion criteria: 1 Pustular psoriasis. 2 Drug induced psoriasis. 3 Patients with Liver disorder. 4 Patients with dyslipidaemia. 5 Hepatitis B/C or HIV infection; patient with lymphoproliferative disorders or malignancy. 6 Patient with Basal/Squamous cell carcinoma or cervical carcinoma in situ. 7 Evidence of prior/ active tuberculosis infection. 8 Use of oral or injectable corticosteroids/ other immunosuppressant s within 4 weeks prior to the first study dose. 9 Pregnancy 10 Lactating female
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the Effectiveness of oral Tofacitinib 5mg twice daily in patients with Psoriasis Vulgaris.Timepoint: Baseline, 1st month, 2nd month and 3rd month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) To study the adverse effects of oral Tofacitinib 5mg twice daily in patients with Psoriasis Vulgaris. 2) To study the quality of life changes in patients with Psoriasis Vulgaris.Timepoint: Baseline, 1st month, 2nd month & 3rd month | — |
Countries
India
Contacts
Government Medical College, Haldwani, Nainital, Uttarakhand