Health Condition 1: S048- Injury of other cranial nerves
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Study population parameters will be include all adult patients (age 18-65), undergoing elective posterior fossa craniotomy, with American Society of Anesthesiologists (ASA) physical status I-III
Exclusion criteria
Exclusion criteria: Exclusion criteria should include patients with a history of chronic pain, prior nerve blocks, allergy to study medications, or contraindications to ultrasound-guided procedures. Randomization should be stratified by age and sex.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome was the OPS score at 12 hours postoperativelyTimepoint: The primary outcome was the OPS score at 12 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes were: (1) OPS scores at 2, 4, 6, 8, 16, and 24 hours postoperatively; (2) duration of analgesia, defined as the time to the first postoperative analgesic request; (3) cumulative intraoperative fentanyl dose; (4) intraoperative heart rate and systolic blood pressure at baseline, skin incision, dural incision, 1-hour postintubation, 2-hour postintubation, 3-hour postintubation, dural closure, and skin closure; (5) postoperative heart rate and systolic blood pressure at 2, 4, 6, 8, 12, 16, and 24-hour post procedure; (6) incidence of postoperative nausea and vomiting, and; (7) incidence of nerve-block complications, namely scalp hematoma or inadvertent subarachnoid or intravascular injection of local anestheticTimepoint: Secondary outcomes were: (1) OPS scores at 2, 4, 6, 8, 16, and 24 hours postoperatively; (2) duration of analgesia, defined as the time to the first postoperative analgesic request; (3) cumulative intraoperative fentanyl dose; (4) intraoperative heart rate and systolic blood pressure at baseline, skin incision, dural incision, 1-hour postintubation, 2-hour postintubation, 3-hour postintubation, dural closure, and skin closure; (5) postoperative heart rate and systolic blood pressure at 2, 4, 6, 8, 12, 16, and 24-hour post procedure; (6) incidence of postoperative nausea and vomiting, and; (7) incidence of nerve-block complications, namely scalp hematoma or inadvertent subarachnoid or intravascular injection of local anesthetic | — |
Countries
India
Contacts
King Georges Medical University Lucknow