Patients undergoing abdominal hysterectomy under spinal anaesthesia will be divided into two groups, one receive bupivacaine with dexmedetomidine and other group receive ropivacaine with dexmedetomidine in transverse abdominis plan block for comparing the efficacy of post operative pain management.

Analgesic efficacy of transverse abdominis plane block with bupivacaine and dexmedetomidine Vs ropivacaine and dexmedetomidine after total abdominal hysterectomy under spinal anaesthesia: A prospective randomised study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086339

Enrollment

Registered

2025-05-05

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N839- Noninflammatory disorder of ovary,fallopian tube and broad ligament, unspecified Health Condition 2: N959- Unspecified menopausal and perimenopausal disorder

Interventions

Intervention1: Transverse abdominis plane block with bupivacaine and dexmedetomidine.: this group will receive 30ml of 0.25% bupivacaine plus 50mcg dexmedetomidine for bilateral transverse abdominis p

Eligibility

Inclusion criteria

Inclusion criteria: a) ASA grade I & II patients b) Patients height 150-160 cm. c) Patients weight 40-60 kgs. d) Patients undergoing elective total abdominal hysterectomy lasting not more than 3 hours under Spinal Anesthesia. e) Patients willing to give informed and written consent

Exclusion criteria

Exclusion criteria: a) Patients with known history of allergy to study drugs used. b) Patients with features of infection over anterior abdominal wall. c) Patient unable to understand VAS (Visual Analogue Score). d) Patient who failed spinal anesthesia and have to convert to general anesthesia for total abdominal hysterectomy.

Design outcomes

Primary

Measure	Time frame
1.To compare the analgesic efficacy of combination of bupivacaine and dexmedetomidine to ropivacaine and dexmedetomidine in TAP (transversus abdominis plane) block after total abdominal hysterectomy via VAS (visual analogue score). 2.To include time to first rescue analgesia. Timepoint: 4hours post surgery 8hours post surgery 12hours post surgery 24hours post surgery	—

Secondary

Measure	Time frame
1. To evaluate hemodynamic changes in post operative period. 2. To assess any incidence of complications.Timepoint: Baseline 4hours post surgery 8hours post surgery 12hours post surgery 24 hours post surgery	—

Countries

India

Contacts

Public ContactDr Manisha Bhagat

Rajendra Institute Of Medical Sciences, Ranchi, Jharkhand, 834009

dipalishio@gmail.com9620310511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026