To seen incidence and severity of patients for postoperative sore throat with pre operative nebulization with ketamine

A Prospective Randomised Controlled Double blind Study to evaluate the effect of preoperative Ketamine nebulization on incidence and severity of postoperative sore throat after general anaesthesia with endotracheal intubation - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086307

Enrollment

146

Registered

2025-05-05

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Ketamine Nebulization: DOSE - 1 ML of Ketamine with 4ML of normal saline ROUTE OF ADMINISTRATION- NEBULIZATION Control Intervention1: NORMAL SALINE NEBULIZATION: DOSE - 5ML NORMAL SALI

Eligibility

Inclusion criteria

Inclusion criteria: 1. Surgery duration less than 3 hours 2. Patients 18 - 60 years 3. ASA grade I, II 4. Patients of either sex 5. All patient undergoing elective surgery under general anaesthesia with ET intubation

Exclusion criteria

Exclusion criteria: 1. Surgery duration less than 3 hours 2. Patients 18 - 60 years 3. ASA grade I, II 4. Patients of either sex 5. All patient undergoing elective surgery under general anaesthesia with ET intubation

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of preoperative ketamine nebulization on (a) incidence of post operative sore throat (b) severity of post operative sore throat Timepoint: At 0 hour 2 hour 4 hour 6 hour 12 hour 24 hour	—

Secondary

Measure	Time frame
To assess the effect on haemodynamic parameters preop & postop 2)To note side effects ,if any Timepoint: Till 24 hours	—

Countries

India

Contacts

Public ContactDr ANURADHA MALLIWAL

D Y PATIL SCHOOL OF MEDICINE

anumalliwal@gmail.com9920318482

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026