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Comparing the Effectiveness and Safety of Platelet-Rich Fibrin vs. Platelet-Rich Plasma Injections in Treating Alopecia Areata

A Comparative study of efficacy and safety of intralesional platelet rich fibrin vs intralesional platelet rich plasma in patients of alopecia areata - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086230
Enrollment
30
Registered
2025-05-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L639- Alopecia areata, unspecified

Interventions

Intervention1: Patients of AA will receive Intralesional Platelet rich fibrin: Half of the patches of AA will receive intralesional injections of platelet rich fibrin prepared in departmental lab. Pre

Sponsors

Dr RPGMC Tanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of AA between Age group 18 to 50 years. 2. Diagnosed clinically with alopecia areata of scalp coming to skin opd. 3. Patients willing to give consent for inclusion in study 4. Patients who have not taken medical treatment for AA in any form for the last 6 months. 5. Control group includes age and sex matched individuals without history of AA 6. Platelet count more than 1.5 lac

Exclusion criteria

Exclusion criteria: 1. Patients with alopecia other than alopecia areata. 2. Patients with active infection at the local site. 3. Patients having keloidal tendency. 4. Patients with blood coagulopathies. 5. Platelet count less than 1.5 lacs per l. 6. Patients who are immunosuppressed (HIV, malignancy, steroid or chemotherapy). 7. Pregnancy or lactation 8. Patients not willing to give written informed consent. 9. Patient on anticoagulation.

Design outcomes

Primary

MeasureTime frame
Investigator assessment scaleTimepoint: Baseline, 2, 4, 6 months

Secondary

MeasureTime frame
Trichoscopic Analysis 1 Size of alopecia patch using measuring tape 2 Location Of alopecia patchTimepoint: Baseline, 2, 4, 6 months;Patients self-assessmentTimepoint: Baseline, 2, 4, 6 months;Improvement assessment based on SALT scoreTimepoint: Baseline, 2, 4, 6 months

Countries

India

Contacts

Public ContactDr Deepak soan

Department of DVL, Dr RPGMC Tanda

hoddermatologytanda@gmail.com9418457647

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026