Comparative Study of Harmonic Scalpel Versus Traditional Suture Ligation for Securing the Appendix Base During Laparoscopic Appendectomy

CLINICAL PROFILE of APPENDICITIS AND COMPARATIVE STUDY FOR USE OF HARMONIC SCALPEL (SEAL AND CUT) AND SUTURE LIGATION OF BASE OF APPENDIX DURING LAPAROSCOPIC APPENDECTOMY - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086194

Enrollment

Registered

2025-05-02

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Harmonic Scalpel: Surgical instrument Ultrasonic energy based device used for sealing as well as cutting the base of appendix. Intervention2: Suture ligation: Absorbable sutures used Co

Eligibility

Inclusion criteria

Inclusion criteria: Patient willing for laparoscopic appendicectomy

Exclusion criteria

Exclusion criteria: Patient with base of appendix highly inflamed / gangrenous Any other intra-abdominal pathology other than acute appendicitis, e.g., appendicular mass, appendicular abscess, tuberculosis, carcinoid tumor, pelvic inflammatory disease, ovarian tumors, ceacal mass, etc. Patients declared unfit for laparoscopic surgery during preoperative assessment Patients having severe co morbid condition COPD/CAD/CHF Diagnostic criteria

Design outcomes

Primary

Measure	Time frame
Position of Appendix Operative time Postoperative leak Postoperative ileus Surgical site infection Hospital StayTimepoint: Intraoperative Postoperative	—

Secondary

Measure	Time frame
Recovery Postoperative complicationsTimepoint: 3 months	—

Countries

India

Contacts

Public ContactApoorva Mathur

GSVM medical college and LLR hospital

yadavgd71@gmail.com9415092218

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026