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To determine the salivary biomarker in children with caries active and caries free children

Quantification and correlation of Salivary Tissue inhibitor matrix metalloproteinases 1 and 2 levels in caries free and caries active children A Randomized Clinical Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086192
Enrollment
40
Registered
2025-05-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K026- Dental caries on smooth surface

Interventions

None listed

Sponsors

DR GADIGI SAMPREETHA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children of 3-6 years of age children with 4 and/or more active carious lesions (S-ECC) children with no caries and parents giving consent for the study

Exclusion criteria

Exclusion criteria: Children who received fluoride topical application during the last month children requiring special health care needs Pulpally involved teeth children who were on antibiotic therapy within the past 3 months children with genetic diseases or syndromes and children on any medications

Design outcomes

Primary

MeasureTime frame
To estimate and correlate tissue inhibitor Matrix metalloproteinase-1 and tissue inhibitor Matrix metalloproteinase-2 in caries free and caries active children using ELISA method.Timepoint: baseline—

Secondary

MeasureTime frame
To estimate & correlate tissue inhibitor matrix metalloproteinase-1 & tissue inhibitor matrix metalloproteinase-2 in caries free & caries active childrenTimepoint: baseline—

Countries

India

Contacts

Public ContactDr GADIGI SAMPREETHA

RAJARAJESWARI DENTAL COLLEGE AND HOSPITAL

umapathygowda@gmail.com9740805217

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026