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Using Your Own blood to Heal Tooth Damage due to decay: A Study on Treatment for Cavities in Adults

Effectiveness of Autologous Platelet Concentrate for Vital Pulp Therapy in Adult Patients with Carious Pulp Exposure- A Randomized Controlled Trial - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086122
Enrollment
30
Registered
2025-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: autologous platelet concentrate(platelet rich fibrin): autologous platelet concentrate(platelet rich fibrin) as vital pulp capping agent in caries exposed mandibular molars Control Inte

Sponsors

Dr Nishanthine C
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 30 healthy participants of age group 18 to 45 years Asymptomatic molars with caries exposure Non tender to percussion. Normal response to cold and electric pulp testing. Radiographic evidence of deep caries near the pulp, with no signs of periodontal ligament thickening, furcation radiolucencies, or periapical pathology

Exclusion criteria

Exclusion criteria: Symptomatic teeth Radiographic evidence of periapical pathology. Negative response to pulp sensibility testing. History of systemic diseases. Periodontally compromised teeth. Patients with bleeding disorders or platelet count less than 150,000 per cubic mm. Poor oral hygiene maintenance. Pregnant or lactating females.

Design outcomes

Primary

MeasureTime frame
Teeth treated are expected to demonstrate three dimensional dentin bridge formation, which is an indicator of pulp preservation and pulp regenerationTimepoint: CBCT analysis will be done before treatment and after 1 year of intervention

Secondary

MeasureTime frame
teeth treated are expected to respond normally to pulp sensibility testing and should demonstrate normal periapical tissues in radiographic assessmentTimepoint: pulp sensibility and radiographic assessment will be done preoperatively and 3,6,9,12 months after intervention

Countries

India

Contacts

Public ContactNishanthine Cruz

sri venkateswara dental college

nishanthineandrews29@gmail.com9443978405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026