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Testing Medication to Reduce Stress and Anxiety: A Study Measuring Saliva Levels of Alpha Amylase and Cortisol Before and After Implant Surgery

Pharmacological intervention for stress and anxiety management by estimating salivary alpha amylase and cortisol levels before and after implant surgery- A randomized crossover clinical trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086101
Enrollment
16
Registered
2025-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases

Interventions

Intervention1: Combination Of Paracetamol and Ibuprofen.: Administration of Combination of Paracetamol 325 mg and Ibuprofen 400 mg is done and the stress and anxiety levels are evaluated. The study du

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Systemically Healthy participants requiring dental implant insertion in bilateral edentulous area.

Exclusion criteria

Exclusion criteria: Pregnant and Lactating mothers, participants with systemic diseases or condition, history of Peptic ulcer, Chronic consumption of analgesics or daily use of strong opoids, allery to paracetamol or combination of paracetamol and ibuprofen.

Design outcomes

Primary

MeasureTime frame
This study will help us to assess the effect of pharmacological intervention in reducing post operative stress and anxiety by estimating salivary alpha amylase and cortisol levels in patients undergoing dental implant surgery.Timepoint: 18 months—

Secondary

MeasureTime frame
Assessment of healing after 7 days will provide superior clinical outcomes after stress and anxiety reduction.Timepoint: 18 months—

Countries

India

Contacts

Public ContactHarsha Pravin Goyal

Government Dental College, Raipur

vinleo76@gmail.com9131144870

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026