To compare the effectiveness of Dexamethasone and magnesium sulphate with ropivacaine for post operative pain assessment in lower segment cesarean section patients using an ultrasound to guide the injection to abdominal muscles.

Magnesium sulphate vs Dexamethasone as an adjuvant to ropivacaine in ultrasound guided transverse abdominis plane block as post operative analgesia in lower segment cesarean section patients.A randomised clinical comparative study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/05/086095

Enrollment

100

Registered

2025-05-01

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Magnesium sulphate 250 mg with ropivacaine 0.25%: Transverse abdominis plane block will be given with 250 mg magnesium sulphate with 0.2% ropivacaine , given immediately in the post-ope

Eligibility

Inclusion criteria

Inclusion criteria: Patients posted for elective Lower segment caesarean section without any other comorbidities and primigravida patients and patient within the age group of 18 to 40 years,Patients under ASA 1&2 ,Patients who have given informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: Patients refusal, with multiple gestations, emergency lower segment cesarean section and patients requiring general anaesthesia and Patients with known allergy or contraindication to Ropivacaine, Magnesium Sulphate or Dexamethasone,Patients with a history of chronic pain or on chronic analgesic therapy,Pre eclampsia patient who received magnesium sulphate therapy,Patients with coagulopathy or on anticoagulant therapy, chronic use of steroid therapy, Patients with infection at the injection site or generalized sepsis,Patients with a Body mass index more than 35,Patients with neurological or psychiatric disorders affecting pain perception or reporting,Patients with pregnancy related complications such as preeclampsia, eclampsia, diabetes mellitus , gestational diabetes, and who are unwilling or unable to comply with post-operative pain assessments,patients with renal, cardiovascular diseases,contraindication to subarachnoid block

Design outcomes

Primary

Measure	Time frame
To evaluate the duration of analgesia of dexamethasone and magnesium sulphate as an adjuvant to 0.2% ropivacaine in Ultrasound Guided Transverse Abdominus Plane Block in Lower segment caesarean patients Timepoint: 2,4,6,8,12,24 hours	—

Secondary

Measure	Time frame
To evaluate the pain scores using a standardized pain scale Visual analogue score at various time intervals post operatively,To measure total doses of rescue analgesia intake in first 24 hours post operatively,To monitor hemodynamic variables-systolic blood pressure,Diastolic blood pressure,Mean arterial pressure,Heart rate,Saturation,To observe any side effects due to drugs Timepoint: 2,4,6,8,12,24 hours	—

Measure

Time frame

To evaluate the pain scores using a standardized pain scale Visual analogue score at various time intervals post operatively,To measure total doses of rescue analgesia intake in first 24 hours post operatively,To monitor hemodynamic variables-systolic blood pressure,Diastolic blood pressure,Mean arterial pressure,Heart rate,Saturation,To observe any side effects due to drugs Timepoint: 2,4,6,8,12,24 hours

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Countries

India

Contacts

Public ContactDivya kesarapu

Institue of medical science and sum hospital

drranjitaacharya@gmail.com8763421899

Outcome results