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Efficacy of Adjuvant Cerebellar Theta Transcranial Alternating Current Stimulation In Cognitive Symptoms of Schizophrenia

Efficacy of Adjuvant Cerebellar Theta Transcranial Alternating Current Stimulation In Cognitive Symptoms of Schizophrenia: An EEG-Based Randomized Sham-Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/05/086093
Enrollment
40
Registered
2025-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F20- Schizophrenia

Interventions

Intervention1: Theta Transcranial Alternating Current Stimulation (tACS), Active: The Strastim 32 (Neuroelectrics) is a wearable device that wirelessly transmits the 32-channel data via Wi-Fi. Its hyb

Sponsors

Central Institute of Psychiatry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosis of schizophrenia (6A20) according to International Classification of Diseases, Eleventh Revision (ICD-11), World Health Organization (WHO). 2. Patients willing to give informed consent. 3. Patients aged between 18-60 years of either sex. 4. Illness duration of more than 2 years. 5. MoCA score less than or equal to 25.

Exclusion criteria

Exclusion criteria: 1. Presence of comorbid neurological or other psychiatric disorder. 2. Presence of comorbid substance use in dependence pattern, except nicotine and caffeine. 3. Patients who have received ECT in past 6 month. 4. Patients not ready to give informed consent.

Design outcomes

Primary

MeasureTime frame
Change in cognitive symptoms in schizophrenia in CANTAB after 20 sessions of theta tACS.Timepoint: Change in cognitive symptoms in schizophrenia in CANTAB after 20 sessions of theta tACS measured at baseline, at 2 weeks and at 6 weeks—

Secondary

MeasureTime frame
Change in relative theta power in EEG after 20 sessions of theta tACS.Timepoint: Change in relative theta power will be noted by measuring at baseline & at 6 weeks.—

Countries

India

Contacts

Public ContactAniruddha Mukherjee

Central Institute of Psychiatry

dr_aniruddha@hotmail.com9474413598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026