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A clinical study to compare the effectiveness of two drugs in providing postoperative pain relief using ultrasound guided block after cesarean section

Comparison of Dexmedetomidine with Magnesium sulphate as an adjuvant to Ropivacaine in Transverse Abdominis block for postoperative analgesia in patients undergoing cesarean section- A Randomised Control trial - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/086073
Enrollment
100
Registered
2025-04-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Ultrasound-guided Transverse Abdominis Plane block using Dexmedetomidine as an adjuvant to Ropivacaine: The block is performed after surgery into the fascial plane between the internal

Sponsors

SRM Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients assessed under ASA 2 undergoing elective cesarean section under subarachnoid block 2.Weight between 50 to 90kg 3.Height between 150cm to 180 cm

Exclusion criteria

Exclusion criteria: 1.Patients who refuse to participate in the study 2.Patients with known drug allergies to study drugs 3.Patients with inadequate spinal blockade or failed spinal anesthesia 4.Surgery prolonging more than 90 minutes 5.Patients with pregnancy induced hypertension, Gestational Diabetes Mellitus

Design outcomes

Primary

MeasureTime frame
To assess the duration of postoperative analgesiaTimepoint: The duration of postoperative analgesia is defined as the time taken from completion of block to the time when patient complaints of pain with VAS score more than or equal to 4

Secondary

MeasureTime frame
to estimate the total requirement of rescue analgesia after the block during first 48 hours of postoperative periodTimepoint: every 2 hours for the first 24 hours post administration of TAP block & every 6 hours for the next 24 hours post administration of TAP block;to compare the hemodynamicsTimepoint: every 2 hours for the first 24 hours post administration of TAP block & every 6 hours for the next 24 hours post administration of TAP block;to compare side effects, if any.Timepoint: every 2 hours for the first 24 hours post administration of TAP block & every 6 hours for the next 24 hours post administration of TAP block

Countries

India

Contacts

Public ContactK Karthik

SRM Medical College Hospital and Research Instiute

karthikk1@srmist.edu.in9444586662

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026