A clinical trial to evaluate the efficacy of Vellarugu Chooranam in Peripheral Neuropathy in Type II Diabtes Mellitus patients

AN OPEN NON-RANDOMIZED SINGLE CENTRIC CLINICAL TRIAL TO EVALUATE THE EFFICACY OF VELLARUGU CHOORANAM IN THE MANAGEMENT OF KARATHAMBA VAATHAM (DIABETIC PERIPHERAL NEUROPATHY) AMONG PATIENTS ATTENDING OPD AT GOVERNMENT SIDDHA MEDICAL COLLEGE HOSPITAL,CHENNAI. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085993

Enrollment

Registered

2025-04-30

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G64- Other disorders of peripheral nervous system

Interventions

Intervention1: Vellarugu Chooranam: The purified ingredients Vellarugu Samoolam(1 part) & Pinju kadukkai (1/8part) will be taken in above mentioned quantity, mildly roasted & finely powdered will be s

Eligibility

Inclusion criteria

Inclusion criteria: If the patients fall under, in any of the following three (2013 WHO Diabetic diagnostic criteria)Blood sugar fasting more than 126 and equal to or less than 200 mg /dl (or) Postprandial Blood Sugar more than 200 mg/dl and equal to or less than 350 mg /dl (or). Glycated hemoglobin (HbA1c) more than 7percentage and less than 13 percentage Michigan Neuropathy Screening Instrument (MNSI) Examination score more than or equal to 2.5 considered positive for neuropathy total score out of 5 and MNSI Questionnaires score more than or equal to 7 considered positive for presence of neuropathy total score out of 15. Patients already under medication for Madhumegam. Already diagnosed DM patients with clinical symptoms

Exclusion criteria

Exclusion criteria: Age more than 60 years Insulin Dependent Diabetes Mellitus Autonomic neuropathy Alcohol-associated neuropathy Nutritional linked neuropathy Secondary Thyroid disorder Uremic neuropathy Subjects with severe systemic illness Subjects who are unwilling or unable to comply with the trial protocol

Design outcomes

Primary

Measure	Time frame
To determine the therapeutic effect of Vellarugu Chooranam for the treatment of Karathamba vaatham (Diabetic Peripheral Neuropathy) patients on the basis of Michigan Neuropathy Screening Instrument (MNSI) and HbA1CTimepoint: 1 year	—

Secondary

Measure	Time frame
To determine the aldose reductase inhibition assay of the Siddha medicine Vellarugu Chooranam through invitro methodTimepoint: 3 Months	—

Countries

India

Contacts

Public ContactDr Isabell rafeeda

Department Of Pothu Maruthuvam,Government Siddha Medical College, Arumbakkam,Chennai.

vrafeeda@yahoo.com9444459047

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026