Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Systemically healthy patients of age 30 to 60 are to be recruited for the study. 2. Ethnic South Indian subjects 3. Control group to include subjects with no signs of periodontal disease and probing sulcus depth of less than or equal to 3mm with no evidence of clinical attachment loss. 4. Test group to include patients with Probing Pocket Depth of more than or equal to 5mm and/or Clinical Attachment Loss of more than or equal to 3mm in greater than 30 percentage of sites with periodontitis. (Stage II/III Periodontitis)
Exclusion criteria
Exclusion criteria: EXCLUSION CRITERIA: 1. Patients with any inflammatory systemic conditions such as diabetes mellitus, rheumatoid arthritis, etc. 2. Patients with immunodeficiency disorders. 3. Patients with local modifiers like food impaction, factitious habits and bruxism. 4. Patients who smoke. 5. Use of orthodontic and prosthetic appliances. 6.Patients who had taken systemic antibiotic, anti-inflammatory, hormonal or other assisted drug therapy in the last 6 months or prior to the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| compare the association of rs1799725 of SOD2 and rs7943316 of CAT gene polymorphism in patients with and without periodontitis and susceptibility of developing periodontitisTimepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India