Health Condition 1: K053- Chronic periodontitis
Conditions
Interventions
Intervention1: Group 2 (NSPT + IH): Receives Individualized homeopathic medicine in centesimal potency customized to each patient, along with non-surgical periodontal therapy (NSPT) comprising of scal
Sponsors
Central Council for Research in Homoeopathy
Eligibility
Inclusion criteria
Inclusion criteria: 1. Individuals aged 30 to 70 years, diagnosed with Stage II, III & IV Periodontitis 2. HbA1c eligibility to include both controlled or uncontrolled diabetic patients. 3. No modification in diabetic medication in the last three months before or during the study.
Exclusion criteria
Exclusion criteria: 1. Patients affected with any systemic conditions known to exert effects of any kind in the study or on the assessed parameters. 2. Patients diagnosed with type 1 diabetes 3. Current Smokers and recent former smokers. 4. Pregnant and lactating females. 5 Any form of periodontal therapy in the previous 6 months. 6. Use of any antimicrobials in the last three months. 7. Any other infections (e.g., Common cold, influenza, ENT infections, etc.) may affect any change in the considered study parameters. 8. Patients undergoing or have undergone radiation therapy in the recent past. 9. Long-standing infections of any kind and patients on chemotherapy 10. Uncontrolled hypertension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on Probing (BOP) Probing Pocket Depth (PPD) Clinical Attachment Level (CAL) Timepoint: baseline, month1, month 3 & month6 | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood glucose levels and HbA1cTimepoint: Baseline, month1, month3, month6;Analysis of specific inflammatory biomarkers (IL-1Beta, IL-6, TNF-alpha, IL-17, and MMP-8) in saliva samplesTimepoint: Baseline,month1, month 3 & month6 ,;Measurement of PINK1/PARKIN proteins in serum samples to explore their levels and any alterations between intervention and control groupsTimepoint: Baseline, month1, month 3 & month6;To assess the Oral Health-Related Quality of Life (OHRQoL), using Oral Health Impact Profile (OHIP).Timepoint: Baseline, month1, month 3 & month6 | — |
Countries
India
Contacts
Public ContactDr Varanasi Roja
SRM Kattankulathur Dental College and Hospital , SRM IST, Kattankulathur, Tamil Nadu, India
Outcome results
None listed