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To evaluate the performance of the heart and response to iv fluids and blood in patients undergoing abdominal operations, using a technique that utilises artery cannulation and another, that requires ultrasonography of the heart.

Correlation between Pulse Pressure Variation (PPV) and Aortic Velocity Time Integral (VTI) variability as measures of fluid responsiveness in patients undergoing major abdominal surgery. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085925
Enrollment
64
Registered
2025-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Internal fluid research grant
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for major elective abdominal surgery requiring invasive monitoring.

Exclusion criteria

Exclusion criteria: • Age under 18 years • BMI under 18 kg per meter square • Severe heart valve disease • Known intra-and/or extracardiac shunt • Pulmonary hypertension • Pregnancy

Design outcomes

Primary

MeasureTime frame
A correlation coefficient between 0.5 -1.0Timepoint: Baseline, every 1 hourly and whenever there s a significant blood loss—

Secondary

MeasureTime frame
Change in cardiac output and stroke volume with fluid bolus, at least 10-15%Timepoint: Baseline, every 1 hourly and whenever there s a significant blood loss—

Countries

India

Contacts

Public ContactSneha Merin David

Christian Medical College, Vellore

cmcrahulpillai@gmail.com9894460758

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026