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Assessing the level of blood supply to the brain using bedside ultrasound through internal cranial blood vessel during severe blood loss in trauma patients: A prospective observational study.

Assessment of cerebral perfusion using Transcranial color doppler during hemorrhagic shock in trauma patients: A prospective observational pilot study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085892
Enrollment
80
Registered
2025-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R571- Hypovolemic shock

Interventions

Intervention1: Nil: Nil

Sponsors

All India Institute of Medical Sciences New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A. Hemorrhagic shock group, Adult patients age more than 18 years presenting with class 3 and 4 hemorrhagic shock after acute injury. B. For the control group, healthy subjects without acute injury.

Exclusion criteria

Exclusion criteria: FOR BOTH HEMORRHAGIC SHOCK AND CONTROL GROUP 1.Suspected traumatic brain injury 2.Pregnancy 3.Failure to get an optimal window for image acquisition 4. Age less than 18 years 5. Known cerebral lesion like ischemic or hemorrhagic cerebrovascular event, neoplasm 6.encephalopathy associated with hyperuricemia, hypernatremia, or hypoglycemia 7.Hepatic encephalopathy 8.Unable to obtain conesnt from LAR

Design outcomes

Primary

MeasureTime frame
Feasibility of bedside Transcranial Color Doppler and establishing baseline TCCD values in hemorrhagic shock patients on arrival to the hospital.Timepoint: Till 1 hour from enrollment after diagnosed as hemorrhagic shock

Secondary

MeasureTime frame
To assess the changes in cerebral vascularity using TCCD during hemorrhagic shock and resuscitation.Timepoint: Till 1 hour from enrollment after diagnosed as hemorrhagic shock;To identify the association of TCCD values with the severity of hemorrhagic shockTimepoint: Till 1 hour from enrollment after diagnosed as hemorrhagic shock;To assess the association of the TCD values with the clinical outcomes of patientsTimepoint: Upto 24 hours, 7 days, and 28 days from the time of enrollment

Countries

India

Contacts

Public ContactDr Kapil Dev Soni

JPNA Trauma centre

kdsoni111@gmail.com9718661658

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026